The 9th Ed. of the Smart Materials and Surfaces - SMS 2024 Conference

Speaker's Details

Prof. Nathalie Mignet

CNRS, INSERM U1022, France

Dr Nathalie Mignet is Research Director at the National Center for Scientific Research (CNRS) in France. She is the leader of the Laboratory Chemical and Biological Technologies for Health located at Université de Paris Cité, at the faculty of Pharmacy.

After a PhD in France in organic chemistry, Dr Mignet was hired by the company Lynx Therapeutics in San Francisco. She then joined the University of Sheffield in UK for one year before being hired by the French biotech company Capsulis to work on onion-based nanoparticles called spherulites. She joined the CNRS as a research Scientist in 2000 to work on non-viral gene delivery. Since then, she expanded her domain of interest from drug delivery systems to nanomedicine designed for triggered delivery or imaging.

With her lab (#Mignet Lab), she is interested in nanomedicine for delivery or imaging going from fundamental to preclinical studies mostly in cancer.

She is also the founder and the former president of the French Society for Nanomedecine, SFNano.

Recent articles:

  1. Do HD, Marie C, Bessoles S, Dhotel H, Seguin J, Larrat B, Doan BT, Scherman D, Escriou V, Hacein-Bey-Abina S, Mignet N, Combination of thermal ablation by focused ultrasound, IL-12 pFAR4 plasmid transfection and lipidic adjuvant provide a distal immune response Exploration of Targeted Anti-tumor Therapy, Explor Target Antitumor Ther. 2022, 3, 398–413, https://10.37349/etat.2022.00090
  2. Rebollo R, Oyoun F, Corvis Y, El-Hammadi MM, Saubamea B, Andrieux K, Mignet N, Alhareth K, Microfluidic Manufacturing of Liposomes: Development and Optimization by Design of Experiment and Machine Learning, ACS Appl. Mater Interfaces 2022, 14, 39736-39745, https://10.1021/acsami.2c06627
  3. Renault-Mahieux M, Mignet N, Seguin J, Alhareth K, Paul M, Andrieux K, Co-encapsulation of flavonoids with anti-cancer drugs: A challenge ahead, Int J Pharm. 2022 Jun 18;623:121942, https://10.1016/j.ijpharm.2022.121942
  4. Ma P, Seguin J, Ly NK, Henríquez LC, Plansart E, Hammad K, Gahoual R, Dhôtel H, Izabelle C, Saubamea B, Richard C, Escriou V, Mignet N, Corvis Y, Designing fisetin nanocrystals for enhanced in cellulo anti-angiogenic and anticancer efficacy, Int. J. Pharm X 2022, 4, 100138, https://10.1016/j.ijpx.2022.100138
  5. Fliedel L, Alhareth K, Seguin J, El-Khashab M, Chissey A, Mignet N, Fournier T, Andrieux K.Influence of Liposomes' and Lipoplexes' Physicochemical Characteristics on Their Uptake Rate and Mechanisms by the Placenta. Int J Mol Sci. 2022, 23, 6299, https://10.3390/ijms23116299