Prof Berret research consists in developing novel functional nanostructures with stimuli-responsive features and biocompatibility. The particles, proteins and other biomacromolecules are elementary bricks of colloidal scaffolds designed for applications. These scaffolds include core-corona structures, clusters of engineered nanoparticles and magnetic nanowires. Based on techniques of assembly at the nanoscale using non-covalent interactions, this approach offers versatility and simplicity for the fabrication of novel nanomaterials with enhanced functionalities. The second objective deals with the applications of these nanoscale materials for medicine and biology. It includes their use as tools for imaging and therapy in living cells and tissues, as well as the study of their cyto- and genotoxicity. In this research, emphasis is put on key features such as interactions, localization and titration of nanomaterials in biological environments.